StatisticsNo statistical methods were used to predetermine the sample size. The experiments were not randomized, and investigators were not blinded...
RNA
The SARS-CoV-2 RNA genome contains a 5′-cap that facilitates translation of viral proteins, protection from exonucleases and evasion of the...
Albert, F. W. & Kruglyak, L. The role of regulatory variation in complex traits and disease. Nat. Rev. Genet. 16,...
Author notesThese authors jointly supervised this work: Omar O. Abudayyeh, Jonathan S. GootenbergAuthors and AffiliationsMcGovern Institute for Brain Research at...
Changes in DNA can lead to the development and progression of cancer. DNA serves as a template for an intermediary...
Researchers at the Salk Institute and King Abdullah University of Science and Technology (KAUST) in Saudi Arabia have discovered a...
Expression and purification of the Dicer-2–R2D2 heterodimerDicer-2 and R2D2 were co-expressed in Sf9 insect cells using the Bac-to-Bac system (Invitrogen)....
Cell lines and culture conditionsThe squamous cell carcinoma cell lines SCC25 and FaDu were obtained from ATCC (https://www.lgcstandards-atcc.org). The patient-derived...
Argonaute proteins use nucleic acid guides to find and bind specific DNA or RNA target sequences. Argonaute proteins can be...
Mitochondria are the power plants of cells, and they contain their own genetic material and RNA molecules. Scientists from the...