Polio endgame finish is in sight

Vaccination has been crucial for the control of certain infectious diseases. However, only two have so far been eradicated — the human disease smallpox and an animal infection called rinderpest. In both cases, the virus responsible was eradicated using a vaccination approach based on a ‘weakened’ version of the infectious virus (termed a live attenuated vaccine). Writing in Nature, Yeh et al.¹ report their development of a live attenuated vaccine that might offer a way to eradicate poliomyelitis (polio).

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