Human tissuesFor the in vitro establishment of clonal organoids from colorectal tissues, healthy mucosal tissues were obtained from surgical specimens...
somatic
Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UKYilong Li, Nicola D. Roberts, Peter J. Campbell, Young Seok Ju, Yilong Li, Iñigo Martincorena, Nicola D. Roberts, Jorge...
The Broad Institute of MIT and Harvard, Cambridge, MA, USAEsther Rheinbay, Jeremiah A. Wala, Ofer Shapira, Grace Tiao, Julian M. Hess, Ziao Lin, Jaegil Kim, Yosef E....
Selkoe, D. J. & Hardy, J. The amyloid hypothesis of Alzheimer’s disease at 25 years. EMBO Mol. Med. 8, 595–608...
Freed, D., Stevens, E. L. & Pevsner, J. Somatic mosaicism in the human genome. Genes 5, 1064–1094 (2014).Article CAS PubMed ...
Cherry, A. B. & Daley, G. Q. Reprogramming cellular identity for regenerative medicine. Cell 148, 1110–1122 (2012).CAS Article PubMed PubMed...
Data reportingNo statistical methods were used to predetermine sample size. The experiments were not randomized and the investigators were not...
1.The Cancer Genome Atlas Research Network. Comprehensive and integrative genomic characterization of hepatocellular carcinoma. Cell 169, 1327–1341 (2017).PubMed Central Article ...
1.Martincorena, I. & Campbell, P. J. Somatic mutation in cancer and normal cells. Science 349, 1483–1489 (2015).ADS CAS PubMed Article ...
1.Wamaitha, S. E. & Niakan, K. K. Human pre-gastrulation development. Curr Top Dev Biol 128, 295–338 (2018).CAS PubMed Article PubMed...