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Nature, Published online: 05 April 2023; doi:10.1038/d41586-023-00727-5
Intracellular machines called ribosomes use messenger-RNA sequences to synthesize proteins. Investigations using single-molecule imaging and cryo-electron microscopy techniques reveal structural and kinetic differences in how human ribosomes function compared with those of bacteria. These differences explain why ribosomes in cell-nucleus-bearing species are slower and more accurate than their bacterial counterparts.
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