May 6, 2024
Swollen axons impair neuronal circuits in Alzheimer’s disease

Swollen axons impair neuronal circuits in Alzheimer’s disease

Nature, Published online: 30 November 2022; doi:10.1038/d41586-022-03800-7

Abnormal protein aggregates are a hallmark of Alzheimer’s disease. It emerges that these plaques cause swellings in neuronal projections called axons that prevent proper circuit function.

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