May 23, 2024
Two-drug trick to target the brain blocks toxicity in the body

Two-drug trick to target the brain blocks toxicity in the body

Nature, Published online: 14 September 2022; doi:10.1038/d41586-022-02892-5

When combined, two drugs alter the activity of a protein complex called target of rapamycin complex 1 such that it is inhibited in the brain but not the body, enabling the treatment of brain tumours in mice without systemic toxicity.

Source link