a,b, DHODH, GPX4 and Vinculin protein levels in different cell lines were determined by western blotting. c–i, Chemical structures of...
inhibition
Jiang, X., Stockwell, B. R. & Conrad, M. Ferroptosis: mechanisms, biology and role in disease. Nat. Rev. Mol. Cell Biol....
MiceAll animal care, procedures and experiments were conducted in accordance with NIH guidelines and approved by the Administrative Panels on...
Competing interests S.F.C. is a consultant for and holds equity interest in Imago Biosciences. J.G.D. consults for Microsoft Research, Servier,...
CLINICAL BRIEFINGS 15 March 2023 Leukaemias characterized by the rearrangement of the gene KMT2A or mutation of the NPM1 gene...
Moes, A. D., van der Lubbe, N., Zietse, R., Loffing, J. & Hoorn, E. J. The sodium chloride cotransporter SLC12A3:...
Holland, N. D., Holland, L. Z. & Holland, P. W. Scenarios for the making of vertebrates. Nature 520, 450–455 (2015).Article ...
Wellcome – MRC Cambridge Stem Cell Institute, Cambridge, UKTeresa Brevini, Stephanie Brown, Scott Dillon, Sagar S. Varankar, Mahnaz Darvish-Damavandi, James A. Heslop, Davide Rossetti, Olivia C. Tysoe, Vasileios...
Administration of a small-molecule drug often leads to systemic pharmacological effects that contribute to both efficacy and toxicity and define...
Mice and generation of mixed bone marrow chimeric miceAll mice used in this study were on a C57BL/6J background. Age-...